Hormone de croissance

Acétate de GHRP-6

CAS # : 87616-84-0

GHRP-6 Acetate is a synthetic growth hormone secretagogue that stimulates natural pulsatile growth hormone release from the pituitary gland by acting as a ghrelin receptor agonist. It promotes muscle growth, enhances fat utilization through lipolysis, accelerates recovery, and modulates appetite. Its unique mechanism mimics the body's natural GH secretory pattern. Available as lyophilized powder with ≥99% purity. Its mechanism mimics the body's natural GH secretory pattern. Available as lyophilized powder with ≥99% purity.

Numéro CAS 87616-84-0
Formule moléculaire C46H56N12O6
Poids moléculaire 873.01 g/mol
Séquence/Composition His-D-Trp-Ala-Trp-D-Phe-Lys-NH2

UGS disponibles

Modèle Spécifications MOQ
ghrp6-5 5ml 1 flacon
ghrp6-10 10ml 1 flacon
ghrp6-20 20ml 1 flacon
Expédition dans les 3 à 5 jours ouvrables
Certificat d'analyse inclus
Qualité garantie

Aperçu du produit

GHRP-6 Acetate (Growth Hormone-Releasing Peptide 6) is a synthetic met-enkephalin analog containing unnatural D-amino acids. It acts as an agonist at the growth hormone secretagogue receptor (GHS-R) and is notable for its dual mechanism of GH pulse induction and appetite modulation through ghrelin receptor activation. Its pulsatile GH release pattern more accurately mimics the body's natural secretory rhythm compared to continuous or exogenous hormone administration.

Mécanisme d'action

GHRP-6 Acetate binds to ghrelin receptors in the pituitary gland, triggering intense GH-pulse release. It stimulates intracellular calcium mobilization and inositol phosphate production. The resulting GH pulses activate downstream signaling including JAK-STAT, MAPK/ERK, and PI3K/Akt pathways, influencing protein synthesis, lipid metabolism, and immune cell function.

Principaux avantages

Muscle Growth Enhancement — Stimulates GH-mediated protein synthesis, promotes satellite cell proliferation for muscle fiber repair and hypertrophy, and increases IGF-1 production. Promotes lipolysis for improved body composition.

Appetite Regulation — Through ghrelin receptor agonism, GHRP-6 produces a marked increase in appetite by activating orexigenic neurons in the arcuate nucleus, increasing both meal frequency and size. Useful for conditions requiring increased caloric intake.

Performance & Recovery — Pulsatile GH release pattern supports enhanced tissue repair, accelerated cellular regeneration, and improved post-exercise recovery. Helps maintain lean mass during intense training periods.

Cellular Influence — GH-pulses activate JAK-STAT, MAPK/ERK, and PI3K/Akt pathways for protein synthesis regulation, improved lipid metabolism, and balanced immune system function.

Références

  1. Korbonits M, et al. Ghrelin — a hormone with multiple functions. *Front Neuroendocrinol.* 2004;25(1):27–68.
  2. Berlanga-Acosta J, et al. Growth hormone releasing peptide-6 (GHRP-6) and other related secretagogue synthetic peptides. *Integr Mol Med.* 2016;3(2):616–623.
  3. Zhao Y, et al. Growth hormone-releasing peptide 6 (GHRP-6) hydrogel for acute kidney injury therapy. *J Nanobiotechnology.* 2025;23(1):62.

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Demande sur mesure
Numéro CAS 87616-84-0
Formule moléculaire C46H56N12O6
Poids moléculaire 873.01 g/mol
Séquence/Composition His-D-Trp-Ala-Trp-D-Phe-Lys-NH2
Acides aminés 6
Formulaire Poudre lyophilisée
La pureté ≥99% par HPLC
Stockage -20°C desséché

Produits apparentés

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