Growth Hormone

GHRP-6 Acetate

CAS #: 87616-84-0

GHRP-6 Acetate is a synthetic growth hormone secretagogue that stimulates natural pulsatile growth hormone release from the pituitary gland by acting as a ghrelin receptor agonist. It promotes muscle growth, enhances fat utilization through lipolysis, accelerates recovery, and modulates appetite. Its unique mechanism mimics the body's natural GH secretory pattern. Available as lyophilized powder with ≥99% purity. Its mechanism mimics the body's natural GH secretory pattern. Available as lyophilized powder with ≥99% purity.

CAS Number 87616-84-0
Molecular Formula C46H56N12O6
Molecular Weight 873.01 g/mol
Sequence/Composition His-D-Trp-Ala-Trp-D-Phe-Lys-NH2

Available SKUs

Model Specification MOQ
ghrp6-5 5ml 1 vial
ghrp6-10 10ml 1 vial
ghrp6-20 20ml 1 vial
Lead time confirmed with quotation
Batch documents available on request
Specifications confirmed before order

Product Overview

GHRP-6 Acetate (Growth Hormone-Releasing Peptide 6) is a synthetic met-enkephalin analog containing unnatural D-amino acids. It acts as an agonist at the growth hormone secretagogue receptor (GHS-R) and is notable for its dual mechanism of GH pulse induction and appetite modulation through ghrelin receptor activation. Its pulsatile GH release pattern more accurately mimics the body's natural secretory rhythm compared to continuous or exogenous hormone administration.

Mechanism of Action

GHRP-6 Acetate binds to ghrelin receptors in the pituitary gland, triggering intense GH-pulse release. It stimulates intracellular calcium mobilization and inositol phosphate production. The resulting GH pulses activate downstream signaling including JAK-STAT, MAPK/ERK, and PI3K/Akt pathways, influencing protein synthesis, lipid metabolism, and immune cell function.

Key Benefits

Muscle Growth Enhancement — Stimulates GH-mediated protein synthesis, promotes satellite cell proliferation for muscle fiber repair and hypertrophy, and increases IGF-1 production. Promotes lipolysis for improved body composition.

Appetite Regulation — Through ghrelin receptor agonism, GHRP-6 produces a marked increase in appetite by activating orexigenic neurons in the arcuate nucleus, increasing both meal frequency and size. Useful for conditions requiring increased caloric intake.

Performance & Recovery — Pulsatile GH release pattern supports enhanced tissue repair, accelerated cellular regeneration, and improved post-exercise recovery. Helps maintain lean mass during intense training periods.

Cellular Influence — GH-pulses activate JAK-STAT, MAPK/ERK, and PI3K/Akt pathways for protein synthesis regulation, improved lipid metabolism, and balanced immune system function.

References

  1. Korbonits M, et al. Ghrelin — a hormone with multiple functions. *Front Neuroendocrinol.* 2004;25(1):27–68.
  2. Berlanga-Acosta J, et al. Growth hormone releasing peptide-6 (GHRP-6) and other related secretagogue synthetic peptides. *Integr Mol Med.* 2016;3(2):616–623.
  3. Zhao Y, et al. Growth hormone-releasing peptide 6 (GHRP-6) hydrogel for acute kidney injury therapy. *J Nanobiotechnology.* 2025;23(1):62.

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CAS Number 87616-84-0
Molecular Formula C46H56N12O6
Molecular Weight 873.01 g/mol
Sequence/Composition His-D-Trp-Ala-Trp-D-Phe-Lys-NH2
Amino Acids 6
Form Lyophilized powder
Purity ≥99% by HPLC
Storage -20°C desiccated
What is the minimum order quantity (MOQ) for GHRP-6 Acetate?
The MOQ is 1 vial per SKU. We supply 5ml, 10ml, and 20ml vials. Bulk kit pricing is available for larger quantities upon request.
What certificate of analysis (COA) is provided with GHRP-6 Acetate?
Each order includes a detailed COA verifying ≥99% purity by HPLC, along with batch-specific molecular weight and sequence confirmation. Additional quality documentation is available upon request.
How is GHRP-6 Acetate shipped and what are the storage conditions?
We ship worldwide using cold-chain logistics to maintain integrity. Upon receipt, store lyophilized powder at -20°C in a desiccated environment. Properly stored, it is stable for the shelf-life indicated on the COA.
Can I request a sample of GHRP-6 Acetate before placing a bulk order?
Small-quantity evaluation samples are available for qualified research institutions and distributors. Please contact our sales team with your organization details to discuss sample availability and terms.
What is the typical lead time for GHRP-6 Acetate orders?
For standard vial quantities, orders typically ship within 3-5 business days after payment confirmation. Bulk or custom orders may have a lead time of 1-2 weeks. Expedited shipping options are available.
What payment methods are accepted for international orders?
We accept wire transfers, major credit cards (Visa, Mastercard), and selected cryptocurrency payments. For established B2B clients, net-30 terms may be arranged after credit review.
Is GHRP-6 Acetate legal to import for research purposes?
GHRP-6 Acetate is supplied for laboratory research use only. Import regulations vary by country; it is the buyer’s responsibility to ensure compliance with all local laws and obtain any necessary permits. We provide documentation to support customs clearance.

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