Growth Hormone

Ipamorelin

CAS #: 170851-70-4

Ipamorelin is a synthetic pentapeptide and selective ghrelin/GHS receptor agonist that stimulates growth hormone release without affecting cortisol, prolactin, or other stress-related hormones. Derived from GHRP-1, it is considered one of the "cleanest" GH secretagogues available. Supports muscle growth, fat metabolism, sleep quality, anti-aging, and joint health. Available as lyophilized powder with ≥99% purity.

CAS Number 170851-70-4
Molecular Formula C38H49N9O5
Molecular Weight 711.85 g/mol
Sequence/Composition Aib-His-D-2Nal-D-Phe-Lys-NH2

Available SKUs

Model Specification MOQ
ipamorelin-5 5ml 1 vial
ipamorelin-10 10ml 1 vial
ipamorelin-20 20ml 1 vial
Lead time confirmed with quotation
Batch documents available on request
Specifications confirmed before order

Product Overview

Ipamorelin (development code NNC 26-0161) is a pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) derived from GHRP-1 that significantly increases plasma growth hormone levels in both animals and humans. Unlike GHRP-2 and GHRP-6, Ipamorelin does not stimulate ACTH or cortisol secretion, making it highly selective for GH release only. It also does not affect prolactin, FSH, LH, or TSH levels.

Mechanism of Action

Ipamorelin mimics the action of natural ghrelin by targeting ghrelin/GHS receptors in the pituitary gland, stimulating growth hormone production and release. Its selectivity means it enhances GH secretion without triggering the stress hormone cascade (cortisol, ACTH), providing "clean" anabolic stimulus without the metabolic side effects of less selective secretagogues.

Key Benefits

Clean GH Stimulation — Selectively increases growth hormone without elevating cortisol, prolactin, or ACTH. This unique selectivity profile minimizes unwanted hormonal side effects.

Muscle Growth & Recovery — Supports lean muscle development, faster recovery from exercise, and reduced muscle soreness through enhanced GH-mediated protein synthesis and tissue repair.

Fat Metabolism — GH elevation promotes lipolysis and fat oxidation, supporting leaner body composition when combined with exercise and proper nutrition.

Sleep Quality — Users report deeper, more restful sleep. GH is primarily released during deep sleep, creating a positive feedback loop between improved sleep and enhanced recovery.

Anti-Aging & Skin Health — Counters age-related GH decline, supporting skin elasticity, hair/nail quality, and overall vitality.

References

  1. Gobburu JV, et al. Pharmacokinetic-pharmacodynamic modeling of ipamorelin in human volunteers. *Pharm Res.* 1999;16(9):1412–1416.
  2. Moulin A, et al. Recent developments in ghrelin receptor ligands. *ChemMedChem.* 2007;2(9):1242–1259.
  3. Ishida J, et al. Growth hormone secretagogues: history, mechanism of action, and clinical development. *JCSM Rapid Commun.* 2020;3(1):25–37.

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CAS Number 170851-70-4
Molecular Formula C38H49N9O5
Molecular Weight 711.85 g/mol
Sequence/Composition Aib-His-D-2Nal-D-Phe-Lys-NH2
Amino Acids 5
Form Lyophilized powder
Purity ≥99% by HPLC
Storage -20°C desiccated
What is the purity of your Ipamorelin?
Our Ipamorelin is guaranteed to be ≥99% pure by HPLC analysis. Each batch undergoes rigorous quality control, and a Certificate of Analysis (COA) documenting actual purity, molecular weight, and sequence is provided with every shipment.
Is this product available in bulk quantities?
Yes, bulk ordering options are available for qualified research institutions and distributors. Standard vial sizes are 5 ml, 10 ml, and 20 ml, with a minimum order quantity of 1 vial. For larger volumes, please contact our sales team for a tailored quotation.
Can I obtain a sample before placing a large order?
Sample requests are handled on a case-by-case basis for established research organizations. Alternatively, small test orders can be placed via our regular ordering process to evaluate product quality.
How is Ipamorelin shipped, and what are the delivery conditions?
We use validated cold-chain packaging with insulated containers and ice packs to ensure product stability during transit. Worldwide shipping is available. Delivery lead times vary by destination; a confirmed timeline is provided upon order confirmation. Customers are responsible for customs clearance, and we supply all necessary documentation including COA and product specs.
What are the recommended storage conditions for this peptide?
Store the lyophilized powder at -20°C in a dry, desiccated environment. After reconstitution, aliquot the peptide solution and store at -20°C or below. Avoid repeated freeze-thaw cycles to maintain stability.
Do you provide a Certificate of Analysis with every order?
Absolutely. A lot-specific COA is included with each purchase, verifying the identity, purity (≥99%), and molecular weight of the Ipamorelin peptide.
What payment methods do you accept for international orders?
We accept major methods including bank wire transfer and other secure payment options. Payment terms are flexible and can be arranged with our sales team to suit institutional or distributor requirements.

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