Hormone de croissance

Ipamorelin

CAS # : 170851-70-4

Ipamorelin is a synthetic pentapeptide and selective ghrelin/GHS receptor agonist that stimulates growth hormone release without affecting cortisol, prolactin, or other stress-related hormones. Derived from GHRP-1, it is considered one of the "cleanest" GH secretagogues available. Supports muscle growth, fat metabolism, sleep quality, anti-aging, and joint health. Available as lyophilized powder with ≥99% purity.

Numéro CAS 170851-70-4
Formule moléculaire C38H49N9O5
Poids moléculaire 711.85 g/mol
Séquence/Composition Aib-His-D-2Nal-D-Phe-Lys-NH2

UGS disponibles

Modèle Spécifications MOQ
ipamorelin-5 5ml 1 flacon
ipamorelin-10 10ml 1 flacon
ipamorelin-20 20ml 1 flacon
Expédition dans les 3 à 5 jours ouvrables
Certificat d'analyse inclus
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Aperçu du produit

Ipamorelin (development code NNC 26-0161) is a pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) derived from GHRP-1 that significantly increases plasma growth hormone levels in both animals and humans. Unlike GHRP-2 and GHRP-6, Ipamorelin does not stimulate ACTH or cortisol secretion, making it highly selective for GH release only. It also does not affect prolactin, FSH, LH, or TSH levels.

Mécanisme d'action

Ipamorelin mimics the action of natural ghrelin by targeting ghrelin/GHS receptors in the pituitary gland, stimulating growth hormone production and release. Its selectivity means it enhances GH secretion without triggering the stress hormone cascade (cortisol, ACTH), providing "clean" anabolic stimulus without the metabolic side effects of less selective secretagogues.

Principaux avantages

Clean GH Stimulation — Selectively increases growth hormone without elevating cortisol, prolactin, or ACTH. This unique selectivity profile minimizes unwanted hormonal side effects.

Muscle Growth & Recovery — Supports lean muscle development, faster recovery from exercise, and reduced muscle soreness through enhanced GH-mediated protein synthesis and tissue repair.

Fat Metabolism — GH elevation promotes lipolysis and fat oxidation, supporting leaner body composition when combined with exercise and proper nutrition.

Sleep Quality — Users report deeper, more restful sleep. GH is primarily released during deep sleep, creating a positive feedback loop between improved sleep and enhanced recovery.

Anti-Aging & Skin Health — Counters age-related GH decline, supporting skin elasticity, hair/nail quality, and overall vitality.

Références

  1. Gobburu JV, et al. Pharmacokinetic-pharmacodynamic modeling of ipamorelin in human volunteers. *Pharm Res.* 1999;16(9):1412–1416.
  2. Moulin A, et al. Recent developments in ghrelin receptor ligands. *ChemMedChem.* 2007;2(9):1242–1259.
  3. Ishida J, et al. Growth hormone secretagogues: history, mechanism of action, and clinical development. *JCSM Rapid Commun.* 2020;3(1):25–37.

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Demande sur mesure
Numéro CAS 170851-70-4
Formule moléculaire C38H49N9O5
Poids moléculaire 711.85 g/mol
Séquence/Composition Aib-His-D-2Nal-D-Phe-Lys-NH2
Acides aminés 5
Formulaire Poudre lyophilisée
La pureté ≥99% par HPLC
Stockage -20°C desséché

Produits apparentés

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