Recovery & Healing

BPC-157

CAS #: 137525-51-0

BPC-157 is a synthetic pentadecapeptide derived from a protective protein found in human gastric juice. It demonstrates remarkable regenerative effects across multiple tissue types including skin, muscle, bone, ligaments, and tendons. Known for exceptional stability in gastric juice (>24 hours), supporting oral administration. Available as lyophilized powder with ≥98% purity.

CAS Number 137525-51-0
Molecular Formula C62H98N16O22
Molecular Weight 1419.53 g/mol
Sequence/Composition GEPPPGKPADDAGLV

Available SKUs

Model Specification MOQ
bpc157-5 5ml 1 vial
bpc157-10 10ml 1 vial
bpc157-20 20ml 1 vial
Lead time confirmed with quotation
Batch documents available on request
Specifications confirmed before order

Product Overview

BPC-157 (Body Protection Compound 157) is a 15-amino acid peptide synthesized using solid-phase peptide synthesis. It is derived from human gastric juice and has been extensively researched for its regenerative and tissue-protective effects. Its remarkable stability in the gastric environment distinguishes it from most peptides, enabling both injectable and oral routes of administration.

Mechanism of Action

BPC-157 activates the VEGFR2 pathway to stimulate angiogenesis and promotes nitric oxide synthesis to improve blood vessel dilation and circulation. It up-regulates growth factors including EGR-1, activates FAK-paxillin complexes for cell migration and cytoskeletal reorganization, and stimulates the JAK-2 signaling pathway for cell survival and immune modulation.

Key Benefits

Angiogenesis & Tissue Repair — Activates the VEGFR2 pathway to promote new blood vessel formation. Enhances nitric oxide production, improving oxygen and nutrient delivery to damaged areas. Clinical evidence shows 7 of 12 patients with chronic knee pain experienced relief lasting over six months after a single BPC-157 injection.

Endothelial Function Support — Modulates caveolin-1 interaction with eNOS through the Src kinase pathway, enabling sustained nitric oxide production and maintained vasodilation for continuous blood flow to healing tissues.

Cellular Signaling & Repair — Activates FAK-paxillin complexes for wound cell migration, stimulates JAK-2 for cell survival, and triggers EGR-1 as a master transcriptional switch for organized healing.

Gut Health Support — As a gastric juice-derived peptide, BPC-157 promotes mucosal integrity throughout the gastrointestinal tract, enhances growth hormone receptor expression, modulates nitric oxide systems for mucosal blood flow, and reduces pro-inflammatory cytokines.

References

  1. Perovic D, et al. Novel therapeutic effects in rat spinal cord injuries by the administration of BPC 157 therapy. *Curr Issues Mol Biol.* 2022;44:1901–1927.
  2. Japjec M, et al. Stable gastric pentadecapeptide BPC 157 as a therapy for the disable myotendinous junctions in rats. *Biomedicines.* 2021;9:1547.
  3. Stuehr DJ, et al. A natural heme deficiency exists in biology that allows nitric oxide to control heme protein functions. *Bioessays.* 2023;45:e2300055.

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CAS Number 137525-51-0
Molecular Formula C62H98N16O22
Molecular Weight 1419.53 g/mol
Sequence/Composition GEPPPGKPADDAGLV
Amino Acids 15
Form Lyophilized powder
Purity ≥99% by HPLC
Storage -20°C desiccated
What is the minimum order quantity for BPC-157?
The minimum order quantity for BPC-157 is one vial, available in 5ml, 10ml, or 20ml specifications. For bulk or wholesale inquiries, please contact our sales team for volume pricing and availability.
Is a Batch documents available on request with BPC-157 orders?
Yes, every order of BPC-157 is accompanied by a Certificate of Analysis (COA) that verifies the product's identity and purity, which is ≥99% as determined by HPLC.
Can I request a sample of BPC-157 for evaluation?
Sample requests may be accommodated for qualified research institutions. Please reach out to our team to discuss your specific requirements and availability.
What is the typical lead time for BPC-157 bulk orders?
Lead times vary based on order volume and destination. For current processing and delivery estimates, please contact us with your order details.
How is BPC-157 shipped, and what about customs handling?
BPC-157 is shipped using cold-chain logistics to ensure stability. International customers are responsible for complying with local import regulations, and we can provide documentation to facilitate customs clearance.
What payment terms are accepted for B2B orders of BPC-157?
We accept bank transfers, major credit cards, and other standard methods. Payment terms may be negotiable for large or recurring orders; please discuss with our sales department.
How should BPC-157 lyophilized powder be stored?
Store the lyophilized powder at -20°C in a desiccator to maintain stability. After reconstitution, researchers typically aliquot and store solutions at -80°C for long-term storage.

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