Brain & Cognitive

Cerebrolysin

Cerebrolysin is a peptide-based neuroprotective mixture derived from porcine brain tissue, containing neurotrophic factors including BDNF, NGF, GDNF, and CNTF. It promotes neurogenesis, neuroplasticity, and neuroprotection by modulating key signaling pathways. Used across Eurasian countries for stroke recovery, dementia, traumatic brain injury, and cognitive enhancement. Available as solution for injection.

Molecular Formula Mixture of neuropeptides
Molecular Weight ~10,000 (mixture) g/mol
Sequence/Composition Polypeptide mixture
Amino Acids Mixture

Available SKUs

Model Specification MOQ
cerebrolysin-5 5ml 1 vial
cerebrolysin-10 10ml 1 vial
cerebrolysin-20 20ml 1 vial
Lead time confirmed with quotation
Batch documents available on request
Specifications confirmed before order

Product Overview

Cerebrolysin (developmental code FPF-1070) is an enzymatically-treated peptide preparation from pig brain containing brain-derived neurotrophic factor, glial cell line-derived neurotrophic factor, nerve growth factor, and ciliary neurotrophic factor. It crosses the blood-brain barrier, and its biological effects mirror those of endogenous neurotrophic factors. It is used clinically in dozens of Eurasian countries for acute and chronic central nervous system disorders.

Mechanism of Action

Cerebrolysin induces neurogenesis, neuroplasticity, and neuroprotection by modulating two key signaling pathways: the Neurotrophic Factor (NTF) Pathway for maintaining and restoring neuronal networks, and the Sonic Hedgehog (Shh) Signaling Pathway for brain organization and structure.

Key Benefits

Neurological Disorder Support — Improves symptoms in autism spectrum disorder, ADHD, and cerebral palsy by modulating neurotransmitter systems and reducing neuroinflammation. Enhances attention span, impulse control, and behavioral regulation.

Cognitive Enhancement — Promotes release of neurotrophic factors (NGF, BDNF) supporting neuronal survival and synaptic plasticity. Modulates cholinergic, dopaminergic, and glutamatergic pathways for improved memory, focus, and information processing.

Cerebral Energy Metabolism — Enhances mitochondrial energy production, supporting the brain's high metabolic demands (approximately 20% of total body energy). Improves ATP availability for synaptic transmission and neurotransmitter synthesis.

Cerebral Blood Flow Improvement — Repairs damaged cerebral microvasculature through angiogenesis promotion, endothelial cell survival enhancement, and blood-brain barrier integrity restoration.

Neuroprotection — Reduces excitotoxicity by modulating glutamate receptors and calcium ion influx. Mitigates oxidative stress by enhancing endogenous antioxidant defenses. Particularly beneficial in acute conditions such as stroke or traumatic brain injury.

References

  1. Muresanu DF, et al. Cerebrolysin and Recovery After Stroke (CARS): A randomized, placebo-controlled, double-blind, multicenter trial. *Stroke.* 2016;47(1):151–159.
  2. Zhang D, et al. Efficacy and safety of Cerebrolysin for acute ischemic stroke: A meta-analysis. *BioMed Res Int.* 2017;2017:4191670.
  3. Fiani B, et al. Cerebrolysin for stroke, neurodegeneration, and traumatic brain injury: review of the literature. *Neurol Sci.* 2021;42(4):1345–1353.

Technical Support

Our team can assist with product, batch-document and procurement questions during business hours.

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Molecular Formula Mixture of neuropeptides
Molecular Weight ~10,000 (mixture) g/mol
Sequence/Composition Polypeptide mixture
Amino Acids Mixture
Form Lyophilized powder
Purity ≥99% by HPLC
Storage -20°C desiccated
What is the purity level of Cerebrolysin and do you provide a Certificate of Analysis?
Cerebrolysin is supplied with a purity of ≥99% as determined by HPLC. A Certificate of Analysis (COA) is included with each order, detailing the batch-specific quality control data.
Are bulk or wholesale quantities available for Cerebrolysin?
Yes, bulk ordering is supported. The product is available in multiple vial sizes (5ml, 10ml, 20ml) with a minimum order quantity of 1 vial per SKU. For larger volume requirements, please contact our sales team to discuss custom quantities and pricing.
Can I obtain a sample of Cerebrolysin for evaluation before placing a larger order?
Sample requests are evaluated on a case-by-case basis. We recommend contacting us with your research institution details to inquire about sample availability for this product.
What is the typical lead time for Cerebrolysin orders?
Lead time depends on the order size and destination. For standard orders, dispatch usually occurs within 3–5 business days after confirmation. Accurate lead times will be quoted upon order placement.
How is Cerebrolysin shipped to ensure stability, and what about customs documentation?
Cerebrolysin is shipped using cold-chain packaging to maintain the required -20°C storage condition. We provide all necessary documentation, including a commercial invoice and proforma documents, to assist with customs clearance. Buyers are responsible for ensuring compliance with their local import regulations.
What are the accepted payment terms for international Cerebrolysin orders?
We accept bank wire transfers (T/T) and major credit cards. For large-volume or recurring orders, flexible payment terms may be arranged. All payments must be cleared before shipment.
How should Cerebrolysin be stored and handled in a research facility?
Cerebrolysin should be stored at -20°C in a desiccated environment. Upon reconstitution, follow standard laboratory protocols for peptide handling, and avoid repeated freeze-thaw cycles to maintain stability.

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